Volume 41 Issue 1
Jan.  2022
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Chunyan Zhao, Shihong Xu, Yifan Liu, Chengcheng Feng, Yongshuang Xiao, Yanfeng Wang, Qinghua Liu, Jun Li. Changes of melatonin and its receptors in synchronizing turbot (Scophthalmus maximus) seasonal reproduction and maturation rhythm[J]. Acta Oceanologica Sinica, 2022, 41(1): 84-98. doi: 10.1007/s13131-021-1923-y
Citation: Chunyan Zhao, Shihong Xu, Yifan Liu, Chengcheng Feng, Yongshuang Xiao, Yanfeng Wang, Qinghua Liu, Jun Li. Changes of melatonin and its receptors in synchronizing turbot (Scophthalmus maximus) seasonal reproduction and maturation rhythm[J]. Acta Oceanologica Sinica, 2022, 41(1): 84-98. doi: 10.1007/s13131-021-1923-y

Changes of melatonin and its receptors in synchronizing turbot (Scophthalmus maximus) seasonal reproduction and maturation rhythm

doi: 10.1007/s13131-021-1923-y
Funds:  The National Natural Science Foundation of China under contract No. 31802319; the Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) under contract No. GML2019ZD0402; the National Key Research and Development Program under contract No. 2018YFD0901204; the Major Agricultural Application Technology Innovation Project of Shandong Province under contract No. SD2019YY011; the Natural Science Foundation of Shandong Province under contract No. ZR2018BC053; the Marine S&T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology (Qingdao) under contract No. 2018SDKJ0502-2; the Fund of China Agriculture Research System under contract No. CARS-47; the Major Science and Technology for Scientific and Technological Innovation Projects (Shandong) under contract No. 2019JZZY020710; the Science and Technology Service Network Initiative Project under contract Nos KFZD-SW-106, ZSSD-019, 2017T3017 and 2019T3022; the Advanced Talents Foundation of Qingdao Agricultural University under contract No. 6631119055.
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  • Corresponding author: E-mail: qinghualiu@qdio.ac.cn; junli@qdio.ac.cn
  • Received Date: 2021-02-02
  • Accepted Date: 2021-05-08
  • Available Online: 2021-11-08
  • Publish Date: 2022-01-10
  • In most fish, reproduction is seasonal or periodic under the suitable conditions. In turbot (Scophthalmus maximus) farms, one of the most economically important marine flatfish species, changes in daylength could cause changes in the spawning time. In this study, to characterize the regulation of reproductive physiology following light signals, three melatonin receptors (Mtnr) investigated in turbot were named smMtnr1, smMtnr2, and smMtnr1c. Distinct expression profiles demonstrated that Mtnr mRNAs were concentrated in the brain (as detected in the hypothalamus (Hy) and mesencephalon (Me)), gonad and eye. The most abundant Mtnr1 and Mtnr2 mRNA expression levels were detected in the central nervous system at the beginning of the breeding season, suggesting that Mtnr1 and Mtnr2 may play vital roles in the regulation of turbot gonadal development. In addition, the melatonin profiles gradually increased and reached to the highest level at the spawning stage, indicating that melatonin is a potent hormone in the regulation of fish oocyte growth and maturation. The results of this study suggested that melatonin is the primary factor that transduces the light signal and regulates the physiological functions of turbot seasonal reproduction. Moreover, the results of this study may establish a foundation for further research seeking to identify fish melatonin receptors involved in the gonadal development and gamete maturation.
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